CBD vs CBN vs CBG vs CBC: What’s the Difference?

It is likely that you are aware that marijuana is a medicinal plant containing several active agents. Cannabidiol is one of them and at the moment much discussed for its beneficial properties. However, there are other cannabinoids in cannabis that are also favorable for your health and well-being, and may be useful if you’d like to get yourself some “weed” with a different variety of cannabinoid-containing drugs? These include cannabichromene (CBC), cannabigerol (CBG), and cannabinol (CBN).

It is still not very clear how cannabis and cannabinoids relate with each other. When one goes deep into studying about cannabinoids, they may encounter various types. CBD, CBN, CBG or CBC are among the common ones that exist widely. But what is the dissimilarity between these compounds with regards to their effect on human health?

The reality is that it becomes difficult sometimes to follow up with the new jargon and literature emerging on these matters. However, it is crucial to comprehend why CBD differs from CBN, CBG or CBC when planning of using marijuana for certain purposes.

Every compound is psychoactive and somatic in nature, thereby posing some importance when determining your choice compound.

What are Cannabinoids?

There exist many chemical compounds in cannabis, but cannabinoids are the most widespread. These chemicals give rise to some special characteristics of the herb, which is also said to be beneficial. People have been using cannabinoids as medicine for ages. Among these cannabinoids are THC and CBD. THC is psychoactive and CBD is not intoxicating.

Cannabinoid is a broad term used to describe chemicals which upon binding to cannabinoid receptors in cells affect the release of neurotransmitters within the brain. It has been found that cannabis contains more than 100 types of cannabinoids which can also be divided into groups depending on what kind of compound it is.

Normally, cannabinoids can be categorized into three main groups namely the phytocannabinoids or those that come from plants, and lastly endocannabinoids which are produced by the human body. Examples of phytocannabinoids are THC, CBD, CBN, CBG, and CBC. These compounds bind to receptors in some cells of the body and lead to different consequences or effects. The receptor types are categorized depending on where they are highly distributed throughout the body central nervous system being one of them.

Cannabigerol (CBG) vs. CBD

CBG, short for cannabigerol, is a hemp cannabinoid that does not make one high. People love it because of its properties such as fighting inflammations, and some studies also suggest that it could be used as an anti cancer compound.

Hemp plant stalks and leaves contain highest amounts of CBG. This implies that including these portions while consuming the plant would offer maximum advantages of CBG.

Potential Health Benefits and Uses of CBG

One of the cannabinoids that are found in large amounts in both hemp and cannabis plants is Cannabigerol (CBG). It occurs in considerable proportions within industrial hemp as well as medical cannabis variations, although it is likely found in trace amounts among most CBD-rich products.

Consumers have grown fond of CBD because of its properties that are able to be used in the body without causing any alteration in mental state. Nevertheless, in your CBG vs CBD, if you expect something more than just anti-inflammatory or antianxiety properties, it might serve as another solution that carries different possible advantages.

Mechanisms of Action of CBG

Cannabigerol (CBG) is known for having anti-inflammatory activity and may be useful in treating pain, anxiety disorders. It also works against cancer.

It acts as a direct agonist of both the CB1 and CB2 receptors meaning that it binds on receptors within the endocannabinoid system of the human body. The ECS controls several physiological functions such as; modulation of moods, monitoring of feeding behaviors, induction or suppression of sleep and waking cycles and finally immunity. Therefore, CBG might be beneficial in disorders related with dysfunction of these systems such as; anxiety, inability to sleep, as well as neurologic diseases like Parkinson’s which some studies have indicated that ECS could be at fault due to reduced endocannabinoids at certain brain sites. Although more research is required to determine whether these compounds will have any significant advantages compared with THC or CBD alone.

Side Effects and Risks of CBG

Despite this, CBG is not an exception; it can cause harm too. Although it is still being studied, some emerging data indicates that it may lead to some side effects such as drowsiness, thirst, loss or increase of appetite. Moreover, CBG might affect the metabolism of some medications, especially cytochromes P450 dependent ones.

Cannabichromene (CBC) vs. CBD

The CBC cannabichromene is also found in marijuana. It is among the less popular cannabinoids, but research indicates that it may be important in one way or another for your health.

In the course of studying the structure and synthesis of THC, researchers uncovered a new compound called Cannabichromene in 1966. The first scientific paper reporting its isolation was by Dr. Raphael Mechoulam from Hebrew University who had taken some samples from hashish provided by Dr. Shimon Ben-Shabat many years earlier and isolated it then. Since then, there have been numerous investigations about CBC properties and effects, and also some information on its uses, although not as much as is known for other cannabinoids such as CBD or CBN.

Potential Health Benefits and Uses of CBC

Cannabichromene (CBC) is a cannabinoid that does not alter the mind. Essentially, it implies that CBC does not result into high moods as THC does; however it may be beneficial in some ways.

In animals models, cannabichromene CBC inhibits pain, reduces inflammation and suppresses convulsions. Studies are ongoing concerning the possibility of using it to treat muscle disorders, as well as inflammation-induced pain among humans.

Mechanisms of Action of CBC

Some researchers have suggested that CBC oil might be a strong antioxidant and therefore protect the body from damages caused by free radicals. Moreover, there are studies one of which indicates that cannabichromene could help in chemotherapy; it kills malignant tumors when they form but does not touch healthy ones.

However, it is still unclear how exactly CBC and its derivatives function as pharmacological agents due to the unidentified nature of their mechanisms. Nevertheless, scientists have a hypothesis that GPR55 receptors may play some role in this process.

Side Effects and Risks of CBC

Although CBC has been less studied than THC and CBD, a few researches indicate that it works with the endocannabinoid system offering properties that help reduce inflammation as well as for pain. Nonetheless, just as in other cannabinoids, CBC may have certain harmful outcomes which include drowsiness, thirsty feeling, and weakness especially at high dosage.

Cannabinol (CBN) vs. CBD

The cannabinoid CBN, or cannabivarin (CBV), is a breakdown byproduct of THC. This compound has properties that cause relaxation hence making it ideal for inducing sleep among the patients with sleep disorders. However, just like the others, it also functions as a separate anti anxiety and anti depressant agent.

Potential Health Benefits and Uses of CBN

CBN is a cannabinoid that could be useful in different illnesses. Studies indicate that it has some pain-relieving effect; by interacting with the endocannabinoid system and therefore reducing pain. Other researches indicate that CBN may as well be beneficial to patients of an inflammatory nature who are chronically sick with diseases such as arthritis and diabetes.

Some researchers also think that CBN, a cannabinoid, could be an effective drug against vomiting and nausea (antiemetics), for which cancer patients have a lot of chemotherapy side effects.

Mechanisms of Action of CBN

CBN is a less popular marijuana compound that many have seen to possess some healing properties, although studies are still going on. There are claims that CBN acts in different ways. One of the major ways includes interaction with the endocannabinoid system(ECS) by binding on cannabinoid receptors CB1 and CB2 with lesser strength than THC. Through this interaction, the compound could cause some changes in the central nervous function such that it has reported hypnotic and analgesic effects. It may also affect the function of TRPV2 receptors, which detect pain and regulate inflammation, among other receptor systems activities. In addition to this, further research is necessary to determine the role played by CBN in comparison to the metabolites of CBN in this regard and hence draw meaningful conclusion about it.

Side Effects and Risks of CBN

CBN, like THC and CBD, can act as an active element in formulating drugs as well as nutritional additions meant for lessening chronic pain, fighting depression, among others. Nevertheless, federal legality of cannabinoid CBN is still not confirmed like its relatives’ federal legality because it causes psychoactivity and for this reason it is prohibited on that level.

Among the usual effects of consuming CBN are sleepiness, lightheadedness as well as sometimes slow cardiovascular activity and low systemic blood flow. Additionally, although in small amounts and lesser than with THC, one might still worry about whether or not CBN (which mostly comes from old or oxidized THC) can make you high.

Choosing the Right Cannabinoid

CBD is highly demanded in the contemporary market being the best non-psychoactive cannabinoid due to its multipurpose nature. However, there are also other three types of cannabinoids namely CBN, found less in the market, CBG and CBC.

Mostly found Cannabinoids – CBD, CBN, CBC. CBD also happens to be one of those cannabinoids that have gained widespread popularity currently due to its non-psychoactive nature which is attributed by “getting high”. 

Your decision should be influenced by factors such as the effects you want, tolerance, and what is legal. When you consult a healthcare provider, they can offer advice tailored to your particular objectives and worries about health. In the end, it is important to choose the perfect cannabinoid for yourself so that you enjoy marijuana as much as possible and in the way you prefer.


Although CBD is among the well-liked cannabinoids today, it is not alone in this category. Every cannabinoid compound has indicated some efficacy towards different disorders and diseases. These compounds differ in their chemical structures and interaction with the human system. Even though both CBD and CBN have proven to be effective for fighting inflammation as well as providing pain relief and other things too, it is possible for one to be superior in certain circumstances or vice versa depending upon what you require!

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